Abstract
Pd(II)-catalyzed meta-olefination of highly electron-deficient arenes is achieved through the use of a rationally designed mutually repulsive ligand. The combination of directed and nondirected C-H functionalization of arenes provides a versatile route for the synthesis of highly sought after 1,2,4-trisubstituted arenes.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry*
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Catalysis
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Electrons
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Hydrocarbons, Aromatic / chemical synthesis
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Hydrocarbons, Aromatic / chemistry*
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Ligands
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Palladium / chemistry*
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Pyridines / chemistry*
Substances
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Alkenes
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Hydrocarbons, Aromatic
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Ligands
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Pyridines
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Palladium