Endothelial protection and viscoelastic retention during phacoemulsification and intraocular lens implantation

Arch Ophthalmol. 1991 Oct;109(10):1438-40. doi: 10.1001/archopht.1991.01080100118055.


Endothelial protection (measured by vital-dye staining and computerized planimetry) and viscoelastic retention during phacoemulsification with and without traumatic lens implantation were assessed in a rabbit model comparing four viscoelastics (Healon, Amvisc Plus, Occucoat, and Viscoat). No significant differences in cell damage were noted between unoperated on controls and groups that underwent atraumatic phacoemulsification with viscoelastic. Cell damage after traumatic lens insertion was reduced significantly by all four viscoelastics. Cell damage with and without traumatic lens implantation was significantly lower when viscoelastics were retained. Viscoat and Occucoat were significantly more likely to be retained than Healon.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cataract Extraction*
  • Cell Count / drug effects
  • Chondroitin Sulfates / therapeutic use*
  • Endothelium, Corneal / drug effects*
  • Endothelium, Corneal / pathology
  • Hyaluronic Acid / therapeutic use*
  • Hypromellose Derivatives
  • Lenses, Intraocular*
  • Methylcellulose / analogs & derivatives*
  • Methylcellulose / therapeutic use
  • Rabbits


  • Hypromellose Derivatives
  • Hyaluronic Acid
  • Methylcellulose
  • Chondroitin Sulfates