Magnetic resonance spectroscopy of the fetal brain

Prenat Diagn. 2009 Apr;29(4):434-41. doi: 10.1002/pd.2248.


Fetal magnetic resonance spectroscopy (MRS) is technically feasible in utero and demonstrates similar findings to those observed in neonatal populations. MRS can provide additional information to conventional T1- and T2-weighted imaging of the fetal brain. It is of particular use when subtle changes are present on conventional fetal MRI sequences, and when imaging fetuses at risk of brain injury and metabolic abnormalities.

Publication types

  • Review

MeSH terms

  • Brain / abnormalities
  • Brain / embryology*
  • Brain / metabolism
  • Brain Chemistry
  • Brain Diseases / diagnosis
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / embryology
  • Female
  • Fetal Growth Retardation / diagnosis
  • Humans
  • Hypoxia-Ischemia, Brain / diagnosis
  • Infant, Newborn
  • Magnetic Resonance Spectroscopy*
  • Metabolism, Inborn Errors / diagnosis
  • Metabolism, Inborn Errors / embryology
  • Pregnancy
  • Prenatal Diagnosis / methods