Familial erythema nodosum

Arthritis Rheum. 1991 Sep;34(9):1177-9. doi: 10.1002/art.1780340915.


Erythema nodosum (EN) is a hypersensitivity reaction associated with many diseases. We describe a family in which 4 sisters had acute or recurrent EN. HLA typing showed a common haplotype in the affected members of the family. A review of familial EN and HLA distribution in EN is presented.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Erythema Nodosum / blood
  • Erythema Nodosum / genetics*
  • Erythema Nodosum / immunology
  • Family Health
  • Female
  • HLA Antigens / immunology
  • Haplotypes / immunology
  • Humans
  • Middle Aged
  • Pedigree
  • Recurrence
  • Serotyping


  • HLA Antigens