Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 41 (4), 494-7

Natural Variation at the DEP1 Locus Enhances Grain Yield in Rice


Natural Variation at the DEP1 Locus Enhances Grain Yield in Rice

Xianzhong Huang et al. Nat Genet.


Grain yield is controlled by quantitative trait loci (QTLs) derived from natural variations in many crop plants. Here we report the molecular characterization of a major rice grain yield QTL that acts through the determination of panicle architecture. The dominant allele at the DEP1 locus is a gain-of-function mutation causing truncation of a phosphatidylethanolamine-binding protein-like domain protein. The effect of this allele is to enhance meristematic activity, resulting in a reduced length of the inflorescence internode, an increased number of grains per panicle and a consequent increase in grain yield. This allele is common to many Chinese high-yielding rice varieties and likely represents a relatively recent introduction into the cultivated rice gene pool. We also show that a functionally equivalent allele is present in the temperate cereals and seems to have arisen before the divergence of the wheat and barley lineages.

Similar articles

See all similar articles

Cited by 208 PubMed Central articles

See all "Cited by" articles


    1. Nature. 2007 Feb 8;445(7128):652-5 - PubMed
    1. Nat Genet. 2008 Aug;40(8):1023-8 - PubMed
    1. Nat Genet. 2008 Jun;40(6):761-7 - PubMed
    1. Nat Genet. 2007 May;39(5):623-30 - PubMed
    1. Science. 2005 Jul 29;309(5735):741-5 - PubMed

Publication types


Associated data

LinkOut - more resources