Biology of allograft incorporation

Clin Sports Med. 2009 Apr;28(2):203-14, vii. doi: 10.1016/j.csm.2008.10.009.


The use of implantation of allograft tissue in sports medicine has risen steadily over the last decade. Allograft tissues offer several advantages over autografts, including reduced donor-site morbidity and decreased operative time, and in some instances, no autograft option exists. However, with allografts, there is a small risk of disease transmission, immunologic rejection, and decreased biologic incorporation. Several techniques to limit these pitfalls and maximize graft incorporation are available, however. This chapter takes an in-depth look at the biology of allograft incorporation and how these techniques affect graft incorporation.

MeSH terms

  • Bone Transplantation
  • Humans
  • Menisci, Tibial / surgery
  • Menisci, Tibial / transplantation*
  • Osteochondritis / surgery
  • Sports Medicine
  • Tendon Transfer
  • Transplantation, Homologous* / immunology
  • Transplantation, Homologous* / methods
  • Transplantation, Homologous* / physiology