MR colonography after oral administration of polyethylene glycol-electrolyte solution

Radiology. 2009 Jun;251(3):901-9. doi: 10.1148/radiol.2513081061. Epub 2009 Mar 24.

Abstract

This prospective study was approved by the local institutional ethics committee, and written informed consent was obtained from all patients. The aim of this study was to determine whether the oral administration of a polyethylene glycol (PEG)-electrolyte solution induces adequate luminal distention for magnetic resonance (MR) colonography to be performed and to assess patient acceptance of this procedure. Fifty-five patients (26 women, 29 men; mean age, 60.5 years +/- 14 [standard deviation]; age range, 40-75 years) who were referred for optical colonoscopy (OC) owing to symptoms and findings that included rectal bleeding, altered bowel habits, and positive fecal occult blood test results participated in this study. Standard bowel preparation was performed 1 day before the procedure. MR colonography was performed and followed by OC on the same day. Before undergoing MR colonography, the patients received 2.0-2.5 L of the PEG-electrolyte solution orally. Adequate distention of all colonic segments was achieved in 50-53 (91%-96%) of patients imaged in the supine position and in 51-53 (93%-96%) of patients imaged in the prone position. Oral administration of the solution yielded uniform luminal darkening and sufficient colonic distention for MR colonography in 91%-96% of patients.

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Colonic Diseases / diagnosis*
  • Colonoscopy
  • Contrast Media / administration & dosage
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meglumine / administration & dosage
  • Middle Aged
  • Organometallic Compounds / administration & dosage
  • Polyethylene Glycols* / administration & dosage
  • Prospective Studies
  • Surface-Active Agents* / administration & dosage

Substances

  • Contrast Media
  • Organometallic Compounds
  • Surface-Active Agents
  • Polyethylene Glycols
  • Meglumine
  • gadoterate meglumine