Behavioral outcomes of extremely low birth weight children at age 8 years

J Dev Behav Pediatr. 2009 Apr;30(2):122-30. doi: 10.1097/DBP.0b013e31819e6a16.


Objective: To describe the prevalence of behavioral problems and symptomatology suggestive of Autism and Asperger's disorders at age 8 years among extremely low birth weight (ELBW, <1 kg) children, born 1992 through 1995.

Method: Parent reports of the behavior of 219 ELBW (mean birth weight, 810 g; gestational age 26 weeks) were compared with 176 normal birth weight children of similar maternal sociodemographic status, sex, and age. Behavior was assessed via the Child Symptom Inventory that includes both Symptom Severity Scores and scores meeting DSM-IV criteria for disorders.

Results: ELBW compared with normal birth weight children had significantly higher mean Symptom Severity Scores for the inattentive, hyperactive, and combined types of attention-deficit hyperactivity disorder (all p < .001) as well as higher scores for Generalized Anxiety (p < .01) and Autistic (p < .001) and Asperger's (p < .01) disorders. When DSM-IV criteria were considered, ELBW children also had significantly higher rates of attention-deficit hyperactivity disorder of the inattentive (10% vs 3%, p < .01) and combined (5% vs 0.6%, p < .05) types.

Conclusions: Attention-deficit hyperactivity disorder, mainly the inattentive type is prevalent among ELBW children. Our findings of an increase in symptoms pertaining to Autistic and Asperger's disorders at school age agree with recent reports of others during early childhood. Early identification and intervention for these problems might improve child functioning and ameliorate parent and child distress.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anxiety Disorders / epidemiology
  • Attention Deficit and Disruptive Behavior Disorders / epidemiology*
  • Child
  • Child Behavior
  • Child Development Disorders, Pervasive / epidemiology*
  • Cohort Studies
  • Female
  • Humans
  • Infant, Extremely Low Birth Weight* / psychology
  • Infant, Newborn
  • Male
  • Neuropsychological Tests