Saccharomycopsis fibuligera and its applications in biotechnology

Biotechnol Adv. Jul-Aug 2009;27(4):423-31. doi: 10.1016/j.biotechadv.2009.03.003. Epub 2009 Mar 27.


Saccharomycopsis fibuligera is found to actively accumulate trehalose from starch and the gene responsible for biosynthesis of trehalose has been cloned and its expression has been characterized. This yeast is also found to secrete a large amount of amylases, acid protease and beta-glucosidase which have highly potential applications in fermentation industry. The genes encoding amylases, acid protease and beta-glucosidase in S. fibuligera have been cloned and characterized. It is also used to produce ethanol from starch, especially cassava starch by co-cultures of Saccharomyces cereviase or Zymomonas mobilis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Amylases / metabolism
  • Aspartic Acid Endopeptidases / metabolism
  • Biotechnology / methods*
  • Ethanol / metabolism
  • Molecular Sequence Data
  • Saccharomycopsis / enzymology*
  • Saccharomycopsis / genetics
  • Sequence Alignment
  • Starch / metabolism
  • Trehalose / metabolism
  • beta-Glucosidase / metabolism


  • Ethanol
  • Starch
  • Trehalose
  • Amylases
  • beta-Glucosidase
  • Aspartic Acid Endopeptidases