Interrelationship between coagulation factor VII and obesity in diabetes mellitus (type 2)

Diabetes Res Clin Pract. 2009 Jun;84(3):e41-4. doi: 10.1016/j.diabres.2009.02.018. Epub 2009 Mar 28.

Abstract

We explored the interrelationships of coagulation FVII activity levels with obesity, leptin and insulin resistance in diabetes mellitus (DM Type 2) and in non-diabetic control subjects. We found FVII hypercoagulant activity levels in DM not associated with obesity, leptin levels or insulin resistance. It was found independently associated with hypertriglyceridemia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / complications
  • Factor VII / metabolism*
  • Fasting
  • Female
  • Glycated Hemoglobin A / metabolism
  • Humans
  • Hypertriglyceridemia / blood*
  • Hypertriglyceridemia / complications
  • Insulin / blood
  • Insulin Resistance
  • Leptin / blood
  • Leukocyte Count
  • Male
  • Middle Aged
  • Obesity / blood*
  • Obesity / complications
  • Reference Values
  • Regression Analysis
  • Sex Characteristics

Substances

  • Glycated Hemoglobin A
  • Insulin
  • Leptin
  • Factor VII