Melanocytic proliferations associated with lichen sclerosus in adolescence

Arch Gynecol Obstet. 2009 Dec;280(6):1039-40. doi: 10.1007/s00404-009-1049-5. Epub 2009 Mar 28.


Lichen sclerosus is found in children with an estimated prevalence of at least 1 in 900. Pigmentation in lichen sclerosus is infrequent and melanocytic proliferations in lichen sclerosis are rare and difficult to interpret. In this report, we describe the case of a prepubertal girl presenting with a junctional melanocytic nevus of the labia minora superimposed by lichen sclerosus. The lesion was completely excised and free margins confirmed by histological examination. After a 3 months course of topical clobetasol treatment the girl remained asymptomatic. No local recurrence was notified with a follow-up time of 12 months.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Child
  • Clobetasol / therapeutic use
  • Female
  • Glucocorticoids / therapeutic use
  • Histocytochemistry
  • Humans
  • Melanocytes / pathology*
  • Nevus, Pigmented / drug therapy
  • Nevus, Pigmented / pathology*
  • Nevus, Pigmented / surgery
  • Vulvar Lichen Sclerosus / drug therapy
  • Vulvar Lichen Sclerosus / pathology*
  • Vulvar Lichen Sclerosus / surgery


  • Glucocorticoids
  • Clobetasol