Surgery improves defective oesophageal peristalsis in patients with gastro-oesophageal reflux

Br J Surg. 1991 Sep;78(9):1095-7. doi: 10.1002/bjs.1800780919.


Postoperative manometry was carried out in 12 patients with gastro-oesophageal reflux associated with hypomotility of the oesophageal body. A Nissen fundoplication was carried out in all patients. After a median follow-up of 3.5 years, patients underwent clinical, endoscopic, radiological, manometric and pH-metric evaluation. Manometric results revealed an overall improvement in oesophageal motor function with an increase in the amplitude of deglutition waves and a decrease in the percentage of deglutitions without response. Six of the patients (one with complete motor failure) recovered normal peristaltic function. Non-specific oesophageal motor disorders may be secondary to gastro-oesophageal reflux and are reversible in nature.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Esophagogastric Junction / physiopathology
  • Esophagus / physiopathology*
  • Female
  • Gastric Fundus / surgery
  • Gastroesophageal Reflux / physiopathology
  • Gastroesophageal Reflux / surgery*
  • Humans
  • Male
  • Manometry
  • Middle Aged
  • Motor Neurons / physiology
  • Peristalsis
  • Postoperative Period