Three novel sesquiterpene glycosides of Sarcandra glabra

Chem Pharm Bull (Tokyo). 2009 Apr;57(4):418-20. doi: 10.1248/cpb.57.418.

Abstract

Three new sesquiterpene glycosides, 8 beta,9 beta-epoxy-4 alpha-hydroxy-5 alpha H-lindan-7(11)-en-8 alpha,12-olide-15-O-beta-D-glucopyranoside (1, sarcaglaboside F), 4 alpha-hydroxy-5 alpha,8 beta H-lindan-7(11)-en-8 alpha,12-olide-15-O-beta-D-glucopyranoside (2, sarcaglaboside G), 4 alpha-hydroxy-5 alpha,8 beta H-eudesman-7(11)-en-8 alpha,12-olide-15-O-beta-D-glucopyranoside (3, sarcaglaboside H), together with five known compounds, chloranoside A (4), sarcaglaboside C (5), dihydrovomifoliol-O-beta-D-glucopyranoside (6), 9-hydroxy-heterogorgiolide (7) and chloranthalactone B (8), were isolated from Sarcandra glabra THUMB. NAKAI. The structures and relative configurations of three new compounds were determined on the basis of their spectroscopic data and chemical evidence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Magnoliopsida / chemistry*
  • Molecular Structure
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*

Substances

  • Drugs, Chinese Herbal
  • Glycosides
  • Sesquiterpenes
  • sarcaglaboside F
  • sarcaglaboside G
  • sarcaglaboside H