Serum lipid changes following laser lipolysis

J Cosmet Laser Ther. 2009 Jun;11(2):74-7. doi: 10.1080/14764170902792173.


Background: Laser lipolysis allows the removal of small volumes of fat with concurrent sub-dermal tissue contraction. However, the physiologic consequences of this procedure are not well documented. The possible effects on serum lipids are not well established.

Objective: This study was undertaken to determine what changes, if any, occurred in serum lipid profiles at different intervals (1 day, 7 days, 2 weeks and 1 month) after the procedure.

Methods: Four consecutive patients were included in the study. In all patients, the right and left hips were treated with a 980-nm diode laser (Osyris Medical, Hellemmes, France). Power was tuned at 18 W. Cumulative energies varied from 22 000 J to 50 150 J. Fasting blood samples were obtained before the procedure and 1 day, 3 days, 2 weeks and 1 month after. A standard lipid profile (total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides) was done using the same laboratory facility for all tests.

Results: Serum cholesterol and triglyceride levels remained in the normal range after laser lipolysis.

Conclusion: Two hypotheses can be proposed: (i) fat elimination is so gradual that an increase in circulating lipid levels is not measurable; (ii) the damaged adipocytes are undergoing apoptosis and being removed by phagocytosis, presumably via activated macrophages.

Publication types

  • Clinical Trial

MeSH terms

  • Hip
  • Humans
  • Lasers, Solid-State / therapeutic use*
  • Lipectomy / methods*
  • Lipids / blood*


  • Lipids