A variant (2;13) translocation in rhabdomyosarcoma

Cancer Genet Cytogenet. 1991 Sep;55(2):191-5. doi: 10.1016/0165-4608(91)90077-8.


Cytogenetic analysis of a right buttock mass from a 5-year-old boy showed translocation between an inverted chromosome 1 and a chromosome 13 as the sole cytogenetic abnormality. The breakpoint 13q14 appears to be the same as in previously reported cases of rhabdomyosarcoma (mostly of the alveolar type), but does not show involvement of 2q37. We suggest that this translocation may be a variant of the classical t(2;13)(q37;q14) found in rhabdomyosarcoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Chromosome Banding
  • Chromosomes, Human, Pair 13*
  • Chromosomes, Human, Pair 2*
  • Genetic Variation*
  • Humans
  • Karyotyping
  • Male
  • Rhabdomyosarcoma / genetics*
  • Translocation, Genetic*