Opium consumption in men and diabetes mellitus in women are the most important risk factors of premature coronary artery disease in Iran

Int J Cardiol. 2010 May 14;141(1):116-8. doi: 10.1016/j.ijcard.2008.11.063. Epub 2009 Apr 5.


We performed this study to compare of CAD risk factors in young male and female in Iran. In an analytic cross-sectional study, two groups of patients were evaluated with and without Coronary artery disease. The result of study suggests that there is a relationship between CAD and diabetes mellitus, increasing level of LDL and lipoprotein A in women, While CAD in men had more relation with smoking and opium use. High prevalence and uncontrolled diabetes mellitus in females and relatively high prevalence of opium consumption in males result in different premature CAD patterns.

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Adult
  • Coronary Artery Disease / epidemiology*
  • Coronary Artery Disease / etiology*
  • Cross-Sectional Studies
  • Diabetes Complications / complications
  • Diabetes Complications / epidemiology
  • Diabetes Mellitus / epidemiology*
  • Female
  • Humans
  • Iran / epidemiology
  • Male
  • Middle Aged
  • Opioid-Related Disorders / complications*
  • Opioid-Related Disorders / epidemiology*
  • Opium / administration & dosage*
  • Risk Factors
  • Sex Factors


  • Opium