Electrical storm in Brugada syndrome successfully treated with orciprenaline; effect of low-dose quinidine on the electrocardiogram

Europace. 2009 May;11(5):665-6. doi: 10.1093/europace/eup070. Epub 2009 Apr 3.


We report a case of an electrical storm occurring in a patient implanted with a cardioverter defibrillator for symptomatic Brugada syndrome. Recurrent ventricular fibrillation was initiated by short-coupled premature ventricular beats of right ventricular origin, associated with a fixed Brugada type 2 electrocardiographic pattern. Low-dose orciprenaline application as an intravenous bolus followed by an infusion inhibited the recurrence of ventricular fibrillation and normalized the electrocardiographic pattern. Low-dose oral quinidine had only a moderate effect on the ST-elevation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Arrhythmia Agents / therapeutic use
  • Brugada Syndrome / therapy*
  • Defibrillators, Implantable*
  • Dose-Response Relationship, Drug
  • Electrocardiography
  • Humans
  • Male
  • Metaproterenol / therapeutic use*
  • Quinidine / therapeutic use*
  • Treatment Outcome
  • Ventricular Fibrillation / drug therapy*
  • Ventricular Fibrillation / physiopathology*


  • Anti-Arrhythmia Agents
  • Metaproterenol
  • Quinidine