Churg-Strauss angiitis. Arguments favoring the responsibility of inhaled antigens

Chest. 1991 Nov;100(5):1472-3. doi: 10.1378/chest.100.5.1472.


A 27-year-old man presented with relapsing vascular limb purpura, pulmonary infiltrates and cranial nerve palsies occurring after exposure to pigeons. A lung biopsy specimen showed Churg-Strauss angiitis. Actinomycetes were observed in pneumocytes. The circumstances preceding clinical manifestations and pathologic findings favored the diagnosis of pulmonary vasculitis as a consequence of inhaled antigen. Recovery was obtained after treatment with prednisone, cyclophosphamide, and plasma exchanges.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Churg-Strauss Syndrome / etiology*
  • Columbidae
  • Humans
  • Hypersensitivity, Delayed / complications*
  • Male