The role of stereotactic radiotherapy in the management of ependymomas

Childs Nerv Syst. 2009 Oct;25(10):1269-73. doi: 10.1007/s00381-009-0879-6. Epub 2009 Apr 9.

Abstract

Introduction: Intracranial ependymomas in children have high rates of recurrence. Salvage therapy typically includes repeat resection, possibly chemotherapy, and re-irradiation. Stereotactic radiosurgery has been used for re-irradiation. It offers the theoretical advantages of delivering a high dose of radiation to a small target, providing a maximum dose to the tumor while avoiding surrounding critical brain structures and previously irradiated tissue.

Discussion: Few reports in the literature describe this technique, with mixed, but not often successful, outcomes.

Publication types

  • Review

MeSH terms

  • Adult
  • Brain / radiation effects
  • Brain / surgery
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / surgery*
  • Child
  • Ependymoma / radiotherapy
  • Ependymoma / surgery*
  • Humans
  • Radiosurgery* / adverse effects
  • Treatment Outcome