Sensory polyneuropathy associated with paclitaxel-eluting coronary stent

Jayashri Srinivasan; H Royden Jones

doi:10.1016/j.jns.2009.02.342

Sensory polyneuropathy associated with paclitaxel-eluting coronary stent

J Neurol Sci. 2009 Sep 15;284(1-2):175-6. doi: 10.1016/j.jns.2009.02.342. Epub 2009 Apr 9.

Authors

Jayashri Srinivasan¹, H Royden Jones

Affiliation

¹ Department of Neurology, Lahey Clinic, 41 Mall Road, Burlington, Massachusetts 01805, United States. jayashri_srinivasan@lahey.org

PMID: 19358999
DOI: 10.1016/j.jns.2009.02.342

Abstract

Paclitaxel is a microtubule-stabilizing chemotherapeutic agent used in ovarian and breast cancer; its principal adverse effect is sensory neuropathy. We describe the occurrence of sensory polyneuropathy after multiple paclitaxel-eluting stents in a patient who may have sub-clinical Sjogrens syndrome.

Publication types

Case Reports

MeSH terms

Aged
Angina, Unstable / complications
Angina, Unstable / drug therapy*
Angina, Unstable / therapy
Angioplasty, Balloon
Coronary Restenosis / prevention & control
Disease Susceptibility
Drug-Eluting Stents / adverse effects*
Humans
Male
Neural Conduction
Paclitaxel / administration & dosage
Paclitaxel / adverse effects*
Paresthesia / chemically induced
Polyneuropathies / chemically induced*
Recurrence
Sensation Disorders / chemically induced*
Sjogren's Syndrome / complications

Substances

Paclitaxel