Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009;12(4):233-44.
doi: 10.1159/000203779. Epub 2009 Feb 20.

A health services research agenda for cellular, molecular and genomic technologies in cancer care

Louise Wideroff  1 , Kathryn A Phillips, Gurvaneet Randhawa, Anita Ambs, Katrina Armstrong, Charles L Bennett, Martin L Brown, Molla S Donaldson, Michele Follen, Sue J Goldie, Robert A Hiatt, Muin J Khoury, Graham Lewis, Howard L McLeod, Margaret Piper, Isaac Powell, Deborah Schrag, Kevin A Schulman, Joan Scott
Affiliations
Review

A health services research agenda for cellular, molecular and genomic technologies in cancer care

Louise Wideroff et al. Public Health Genomics. 2009.

Abstract

Background: In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care.

Methods: In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care.

Results: This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations.

Conclusions: Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Moses H, Dorsey ER, Matheson DH, Thier SO. Financial anatomy of biomedical research. JAMA. 2005;294:1333–1342. - PubMed
    1. Kelloff GJ, Lippman SM, Dannenberg AJ, Sigman CC, Pearce HL, Reid BJ, et al. Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer – a plan to move forward. Clin Cancer Res. 2006;12:3661–3697. - PubMed
    1. Deverka PA, Doksum T, Carlson RJ. Integrating molecular medicine into the US health-care system: opportunities, barriers, and policy challenges. Clin Pharmacol Ther. 2007;82:427–434. - PubMed
    1. American Society of Clinical Oncology American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility. J Clin Oncol. 2003;21:2397–2406. - PubMed
    1. Mueller NE, Birmann BM, Parsonnet J, Schiffman MH, Stuver SO. Infectious agents. In: Schottenfeld D, Fraumeni JF, editors. Cancer Epidemiology and Prevention. New York: Oxford University Press; 2006. pp. 507–548.

Publication types