Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jun 1;25(11):1431-2.
doi: 10.1093/bioinformatics/btp242. Epub 2009 Apr 15.

LS-SNP/PDB: Annotated Non-Synonymous SNPs Mapped to Protein Data Bank Structures

Affiliations
Free PMC article

LS-SNP/PDB: Annotated Non-Synonymous SNPs Mapped to Protein Data Bank Structures

Michael Ryan et al. Bioinformatics. .
Free PMC article

Abstract

Summary: LS-SNP/PDB is a new WWW resource for genome-wide annotation of human non-synonymous (amino acid changing) SNPs. It serves high-quality protein graphics rendered with UCSF Chimera molecular visualization software. The system is kept up-to-date by an automated, high-throughput build pipeline that systematically maps human nsSNPs onto Protein Data Bank structures and annotates several biologically relevant features.

Availability: LS-SNP/PDB is available at (http://ls-snp.icm.jhu.edu/ls-snp-pdb) and via links from protein data bank (PDB) biology and chemistry tabs, UCSC Genome Browser Gene Details and SNP Details pages and PharmGKB Gene Variants Downloads/Cross-References pages.

Figures

Fig. 1.
Fig. 1.
Screenshot of rs11604921. (a) Location in PDB 1ci4A. (b) Protein surface rendering colored by conservation; and (c) colored by electrostatic potential.

Similar articles

See all similar articles

Cited by 36 articles

See all "Cited by" articles
Feedback