FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions

Genome Biol. 2009;10(4):R39. doi: 10.1186/gb-2009-10-4-r39. Epub 2009 Apr 19.


EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets that requires minimal development for new data types and search patterns. The FANTOM4 EdgeExpress database summarizes gene expression patterns in the context of alternative promoter structures and regulatory transcription factors and microRNAs using intuitive gene-centric and sub-network views. This is an important resource for gene regulation in acute myeloid leukemia, monocyte/macrophage differentiation and human transcriptional networks.

MeSH terms

  • Acute Disease
  • Cell Differentiation / genetics
  • Computational Biology / methods
  • Computational Biology / statistics & numerical data
  • Databases, Genetic*
  • Gene Expression Profiling / methods
  • Gene Expression Profiling / statistics & numerical data*
  • Gene Regulatory Networks / genetics*
  • Genomics / methods
  • Genomics / statistics & numerical data
  • Humans
  • Internet
  • Leukemia, Myeloid / genetics
  • MicroRNAs / genetics
  • Promoter Regions, Genetic / genetics
  • Software


  • MicroRNAs