Polymorphism of complement component I in Mongoloid populations: a new genetic variant IF A2

Hum Hered. 1991;41(3):206-8. doi: 10.1159/000154002.

Abstract

The genetic polymorphism of the complement component I (IF) was investigated in 282 Chinese, 239 Koreans and 198 Japanese. The 3 common IF phenotypes (A, AB and B) and a new rare IF phenotype (BA2) were observed. The obtained allele frequencies are as follows: IF*A = 0.0993 and IF*B = 0.9007 in Chinese; IF*A = 0.0921 and IF*B = 0.9079 in Koreans; IF*A = 0.0985, IF*B = 0.8990 and IF*A2 = 0.0025 in Japanese. These 3 Mongoloid populations showed a much higher degree of IF polymorphism than Caucasian populations.

MeSH terms

  • Alleles
  • Asian People / genetics*
  • China
  • Fibrinogen / genetics*
  • Genetic Variation / genetics*
  • Humans
  • Japan
  • Korea
  • Phenotype
  • Polymorphism, Genetic / genetics*

Substances

  • Fibrinogen