The BAR domain superfamily: membrane-molding macromolecules

Cell. 2009 Apr 17;137(2):191-6. doi: 10.1016/j.cell.2009.04.010.


Membrane-shaping proteins of the BAR domain superfamily are determinants of organelle biogenesis, membrane trafficking, cell division, and cell migration. An upsurge of research now reveals new principles of BAR domain-mediated membrane remodeling, enhancing our understanding of membrane curvature-mediated information processing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Membrane / chemistry
  • Cell Membrane / ultrastructure
  • Cytoskeleton / metabolism
  • GTP Phosphohydrolases / metabolism
  • Humans
  • Membrane Proteins / chemistry
  • Membrane Proteins / metabolism*
  • Membrane Proteins / ultrastructure
  • Protein Structure, Tertiary


  • Membrane Proteins
  • GTP Phosphohydrolases