Interplay between the heat shock response and translation in Escherichia coli

Res Microbiol. 2009 May;160(4):288-96. doi: 10.1016/j.resmic.2009.03.007. Epub 2009 Apr 18.


It is widely accepted that the heat shock response is critical for quality control of mature proteins. This function is carried out mainly by chaperones and proteases. Recently, a new group of conserved heat shock proteins essential for growth at high temperature has been characterized. These proteins are involved in regulating and maintaining efficient translation under heat shock.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptation, Physiological / genetics
  • Bacterial Proteins / metabolism
  • Escherichia coli / metabolism*
  • Gene Expression Regulation, Bacterial
  • Heat-Shock Response*
  • Metabolic Networks and Pathways
  • Molecular Chaperones / physiology
  • Peptide Hydrolases / physiology
  • Protein Biosynthesis*


  • Bacterial Proteins
  • Molecular Chaperones
  • Peptide Hydrolases