Plasmodium vivax malaria presenting with severe thrombocytopenia, cerebral complications and hydrocephalus

Indian J Pediatr. 2009 May;76(5):551-2. doi: 10.1007/s12098-009-0087-0. Epub 2009 Apr 23.

Abstract

Two cases of a one and 4 year old child of plasmodium vivax malaria are reported in association with CNS complications. Both presented with encephalopathy and seizures. One had severe thrombocytopenia, massive intracranial bleed and hydrocephalus requiring shunt surgery while the other had gastrointestinal manifestations, encephalopathy and hydrocephalus. Both responded to quinine but are left with sequelae.

Publication types

  • Case Reports

MeSH terms

  • Antimalarials / therapeutic use
  • Central Nervous System Protozoal Infections / diagnosis*
  • Central Nervous System Protozoal Infections / therapy
  • Child, Preschool
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Follow-Up Studies
  • Humans
  • Hydrocephalus / diagnosis*
  • Hydrocephalus / surgery
  • Infant
  • Malaria, Vivax / diagnosis*
  • Malaria, Vivax / drug therapy
  • Male
  • Platelet Transfusion / methods
  • Risk Assessment
  • Severity of Illness Index
  • Thrombocytopenia / diagnosis*
  • Thrombocytopenia / therapy
  • Ventriculoperitoneal Shunt / methods

Substances

  • Antimalarials