Accuracy of ultrasonography with color Doppler in ovarian tumor: a systematic quantitative review

Int J Gynecol Cancer. 2009 Feb;19(2):230-6. doi: 10.1111/IGC.0b013e31819c1369.


A quantitative systematic review was performed to estimate the accuracy ultrasonography with color Doppler in the diagnosis of ovarian tumors. Studies that compared color Doppler ultrasonography with paraffin-embedded sections parameters for the diagnosis of ovarian tumors were included. Twelve studies were analyzed, which included 2398 women. The pooled sensitivity was 0.87 (95% confidence interval [CI], 0.84-0.90); and the specificity was 0.92 (95% CI 0.87-0.90). The diagnostic odds ratio for ovarian cancer and borderline lesions vs benign lesions was 125 (95% CI, 55-283). Summary receiver operating characteristic curves were constructed because of heterogeneity in the diagnostic odds ratio. For malignant ovarian cancer and borderline versus benign lesions, the area under the curve was 0.9577. In conclusion, ultrasonography with color Doppler is a useful preoperative test for predicting the diagnosis of pelvic masses.

Publication types

  • Comparative Study
  • Review
  • Systematic Review

MeSH terms

  • Female
  • Humans
  • Odds Ratio
  • Ovarian Neoplasms / diagnostic imaging*
  • Ovarian Neoplasms / pathology
  • Predictive Value of Tests
  • ROC Curve
  • Sensitivity and Specificity
  • Ultrasonography, Doppler, Color*