Encapsulation and sustained release of curcumin using superparamagnetic silica reservoirs

Chemistry. 2009 Jun 2;15(23):5661-5. doi: 10.1002/chem.200802747.

Abstract

For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe(3)O(4) particles surrounded by a silica matrix.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Curcumin / administration & dosage*
  • Drug Delivery Systems*
  • Ferric Compounds / chemical synthesis*
  • Ferric Compounds / chemistry
  • Nanoparticles / therapeutic use
  • Silicon Dioxide / chemistry*
  • Water

Substances

  • Ferric Compounds
  • Water
  • ferric oxide
  • Silicon Dioxide
  • Curcumin