Abstract
The "trick" to carrying out regiocontrolled aminations of allylic alcohols in water as the only medium is use of a nanomicelle's interior as the organic reaction solvent. When HCO(2)Me is present, along with the proper base and source of catalytic Pd, allylic amines are cleanly formed at room temperature.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Allyl Compounds / chemical synthesis
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Allyl Compounds / chemistry*
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Amination
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Amines / chemical synthesis*
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Amines / chemistry
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Catalysis
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Combinatorial Chemistry Techniques
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Molecular Structure
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Palladium / chemistry
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Stereoisomerism
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Temperature
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Water / chemistry
Substances
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Allyl Compounds
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Amines
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Water
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Palladium