A case of juxtaglomerular cell tumor with novel histologic features

Int J Surg Pathol. 2011 Feb;19(1):65-70. doi: 10.1177/1066896909333416. Epub 2009 Apr 29.

Abstract

Juxtaglomerular cell tumors constitute a very small group among the renal neoplasms. Most secrete renin, causing hypertension and hypokalemia due to secondary hyperaldosteronism. They have characteristic pathological features. For the accurate evaluation, diagnosis has to be confirmed by immunohistochemical staining for renin or electron microscopic demonstration of renin protogranules. This report presents a case of renal juxtaglomerular cell tumor in a 63-year-old man with previously unreported histological findings in addition to classic morphology.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Immunohistochemistry
  • Juxtaglomerular Apparatus / metabolism
  • Juxtaglomerular Apparatus / pathology*
  • Kidney Neoplasms / metabolism
  • Kidney Neoplasms / pathology*
  • Male
  • Middle Aged
  • Renin / metabolism*

Substances

  • Renin