Impact of gender and age on in vivo virtual histology-intravascular ultrasound imaging plaque characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] registry)

Am J Cardiol. 2009 May 1;103(9):1210-4. doi: 10.1016/j.amjcard.2009.01.031. Epub 2009 Mar 13.

Abstract

Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (<58, 58 to 68, and >68 years) and again divided according to gender. In conclusion, (1) both women and men had an increase in plaque with increasing age; (2) at any age, men had more plaque than women; (3) percentages of dense calcium and necrotic core increased with increasing patient age in both men and women; and (4) gender differences were lowest in the oldest tercile (>68 years).

Publication types

  • Comparative Study

MeSH terms

  • Age Factors
  • Aged
  • Analysis of Variance
  • Biopsy, Needle
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / pathology*
  • Female
  • Humans
  • Immunohistochemistry
  • Incidence
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Probability
  • Prognosis
  • Registries*
  • Risk Assessment
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Sex Factors
  • Survival Analysis
  • Ultrasonography, Interventional*
  • User-Computer Interface*