Sampling uncertainty in medical research

Osteoarthritis Cartilage. 2009 Nov;17(11):1416-9. doi: 10.1016/j.joca.2009.04.007. Epub 2009 Apr 17.


Statistical analysis is ubiquitous in medical research, but fundamental statistical principles are not always well understood, which has negative effects for both authors and readers of scientific papers. The purpose of this brief review is to provide a methodological overview on populations, samples, analysis units and sampling uncertainty to facilitate an increased understanding of statistical concepts.

Publication types

  • Review

MeSH terms

  • Biomedical Research / statistics & numerical data*
  • Clinical Trials as Topic
  • Data Interpretation, Statistical
  • Humans
  • Osteoporosis / epidemiology*
  • Periodicals as Topic
  • Publishing / statistics & numerical data*
  • Statistics as Topic