Effects of restless legs syndrome (RLS) on sleep

Neuropsychiatr Dis Treat. 2006 Dec;2(4):513-9. doi: 10.2147/nedt.2006.2.4.513.


Restless legs syndrome (RLS) is a common neurological disorder characterized by an irresistible urge to move the legs, usually accompanied or caused by uncomfortable sensations in the legs. Symptoms are worse in the evening or at night than during the day and generally begin or worsen during periods of rest or inactivity. The chronic sleep disturbance often associated with RLS is likely due, at least in part, to the circadian nature of the symptoms. The relationship between disturbed sleep and reduced daytime functioning is well known and thus the accurate diagnosis and effective management of RLS is imperative.

Keywords: RLS; circadian; reduced daytime functioning; restless legs syndrome; sleep disturbance.