Labyrinthitis ossificans in a child with sickle cell disease: CT and MRI findings

Pediatr Radiol. 2009 Sep;39(9):999-1001. doi: 10.1007/s00247-009-1286-6. Epub 2009 May 5.


The association between sensorineural hearing loss and sickle cell disease has been described, and labyrinthine hemorrhage has been reported with sickle cell disease. We report the CT and MRI findings of labyrinthitis ossificans in a child with sickle cell disease who presented with sensorineural hearing loss. Labyrinthitis ossificans is associated with an infectious, inflammatory, or destructive insult to the membranous labyrinth; however, it has not been specifically described with sickle cell disease. Recognition of this condition is important because it affects both management and prognosis of this disease.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / diagnosis*
  • Child
  • Diagnosis, Differential
  • Hearing Loss, Sensorineural / diagnosis*
  • Hearing Loss, Sensorineural / etiology*
  • Humans
  • Labyrinthitis / diagnosis*
  • Labyrinthitis / etiology*
  • Magnetic Resonance Imaging / methods*
  • Male