Recurrent aphthous stomatitis. A study of the clinical characteristics of lesions in 93 cases

J Oral Pathol Med. 1991 Sep;20(8):395-7. doi: 10.1111/j.1600-0714.1991.tb00952.x.


We studied the clinical characteristics of 93 patients with recurrent aphthous stomatitis (RAS); 66 corresponded to minor aphthae (MiRAS), 20 to major aphthae (MaRAS), and 7 to herpes-like ulcerations (HU). MiRAS was seen to present the lowest rate of recurrences, as well as the shortest duration and the fewest lesions per episode. In turn, MaRAS presented the longest duration per recurrence, along with a number of lesions and recurrences that was lower than in HU but greater than in cases of MiRAS. Finally, HU developed the greatest number of lesions and recurrences. When we classified RAS according to the rate of episodes, no statistically significant differences were observed among the three types in terms of patient age, number and duration of lesions, or evolution time of the oral disorder.

MeSH terms

  • Adult
  • Age Factors
  • Female
  • Humans
  • Male
  • Periodicity
  • Recurrence
  • Regression Analysis
  • Stomatitis, Aphthous / classification
  • Stomatitis, Aphthous / pathology*
  • Stomatitis, Aphthous / physiopathology
  • Time Factors