Anticardiolipin antibodies and lupus anticoagulant in Chinese patients with systemic lupus erythematosus

J Rheumatol. 1991 Aug;18(8):1187-92.

Abstract

Ninety-one consecutive patients with systemic lupus erythematosus (SLE) were studied. Forty-two patients had positive anticardiolipin antibodies (aCl) 40 aCl-IgG (44.4%); 4 aCl-IgA (4.4%); 1 aCl-IgM (1.1%). One patient had both aCl-IgG and aCl-IgA and 1 patient had aCl-IgG, aCl-IgA and aCl-IgM. Ten patients (11.1%) had lupus anticoagulant (LA). Both aCl isotypes and LA had no statistical association with thrombosis or thrombocytopenia.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibodies / analysis*
  • Antibodies / immunology
  • Cardiolipins / immunology*
  • Cross-Sectional Studies
  • Female
  • Hong Kong / epidemiology
  • Humans
  • Immunoenzyme Techniques
  • Immunoglobulin A / analysis
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Lupus Coagulation Inhibitor / analysis*
  • Lupus Erythematosus, Systemic / epidemiology
  • Lupus Erythematosus, Systemic / immunology*
  • Male
  • Middle Aged
  • Prospective Studies
  • Thrombocytopenia / epidemiology

Substances

  • Antibodies
  • Cardiolipins
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • Lupus Coagulation Inhibitor