Prebiotic effect of lacto-N-biose I on bifidobacterial growth

Biosci Biotechnol Biochem. 2009 May;73(5):1175-9. doi: 10.1271/bbb.80697. Epub 2009 May 7.

Abstract

We demonstrated the prebiotic effect of lacto-N-biose I (Galbeta1-3GlcNAc) on bifidobacteria in vitro. Lacto-N-biose I, a building unit of the type-I milk oligosaccharides, enhanced the growth of many bifidobacteria, especially Bifidobacterium bifidum, B. breve, and B. longum, which are predominant in the intestines of breast-fed infants. It might be a substantial, natural prebiotic in human colostrums.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylglucosamine / analogs & derivatives*
  • Acetylglucosamine / metabolism
  • Acetylglucosamine / pharmacology
  • Animals
  • Bifidobacterium / drug effects*
  • Bifidobacterium / growth & development*
  • Colostrum / metabolism
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Infant
  • Pregnancy

Substances

  • galactosyl-1,3-N-acetylglucosamine
  • Acetylglucosamine