Screening for novel regulators of embryonic stem cell identity

Cell Stem Cell. 2009 May 8;4(5):377-8. doi: 10.1016/j.stem.2009.04.006.

Abstract

Two recent studies, including one in this issue of Cell Stem Cell, have identified novel regulators of embryonic stem cell (ESC) self-renewal using genome-wide RNAi screens in mouse ESCs (Ding et al., 2009; Hu et al., 2009) and have further expanded the repertoire of factors that regulate ESC identity.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Differentiation
  • Embryonic Stem Cells / cytology*
  • Embryonic Stem Cells / metabolism
  • Gene Expression Profiling
  • Genome
  • Mice
  • RNA, Small Interfering / metabolism*
  • Transcription Factors / metabolism

Substances

  • RNA, Small Interfering
  • Transcription Factors