Barriers to and determinants of medication adherence in hypertension management: perspective of the cohort study of medication adherence among older adults

Med Clin North Am. 2009 May;93(3):753-69. doi: 10.1016/j.mcna.2009.02.007.


Low adherence to antihypertensive medication remains a public health challenge. Understanding barriers to, and determinants of, adherence to antihypertensive medication may help identify interventions to increase adherence and improve outcomes. The Cohort Study of Medication Adherence in Older Adults is designed to assess risk factors for low antihypertensive medication adherence, explore differences across age, gender, and race subgroups, and determine the relationship of adherence with blood pressure control and cardiovascular outcomes over time. This article discusses the relevance of this study in addressing the issue of barriers to anithypertensive medication adherence.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / therapeutic use*
  • Cohort Studies
  • Data Collection
  • Female
  • Health Services Accessibility*
  • Health Services Needs and Demand*
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / epidemiology
  • Hypertension / prevention & control
  • Male
  • Medication Adherence*
  • Racial Groups
  • Risk Factors


  • Antihypertensive Agents