Intracerebral haemorrhage

Lancet. 2009 May 9;373(9675):1632-44. doi: 10.1016/S0140-6736(09)60371-8.


Intracerebral haemorrhage is an important public health problem leading to high rates of death and disability in adults. Although the number of hospital admissions for intracerebral haemorrhage has increased worldwide in the past 10 years, mortality has not fallen. Results of clinical trials and observational studies suggest that coordinated primary and specialty care is associated with lower mortality than is typical community practice. Development of treatment goals for critical care, and new sequences of care and specialty practice can improve outcome after intracerebral haemorrhage. Specific treatment approaches include early diagnosis and haemostasis, aggressive management of blood pressure, open surgical and minimally invasive surgical techniques to remove clot, techniques to remove intraventricular blood, and management of intracranial pressure. These approaches improve clinical management of patients with intracerebral haemorrhage and promise to reduce mortality and increase functional survival.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Algorithms
  • Anticoagulants / adverse effects
  • Brain Edema / etiology
  • Cerebral Amyloid Angiopathy / complications
  • Cerebral Hemorrhage* / diagnosis
  • Cerebral Hemorrhage* / epidemiology
  • Cerebral Hemorrhage* / etiology
  • Cerebral Hemorrhage* / therapy
  • Decision Trees
  • Disease Progression
  • Early Diagnosis
  • Global Health
  • Hemostatics / therapeutic use
  • Humans
  • Hypertension / complications
  • Incidence
  • Magnetic Resonance Imaging
  • Neuroprotective Agents / therapeutic use
  • Public Health
  • Risk Factors
  • Stroke / etiology
  • Tomography, X-Ray Computed


  • Anticoagulants
  • Hemostatics
  • Neuroprotective Agents