Uptake of glycerol-2-phosphate via the ugp-encoded transporter in Escherichia coli K-12

J Bacteriol. 2009 Jul;191(14):4667-70. doi: 10.1128/JB.00235-09. Epub 2009 May 8.


During phenotypic characterization of various Escherichia coli mutants, we observed that DeltaphoA strains are capable of using glycerol-2-phosphate (G2P) as a sole source of phosphorus. Mutations in the ugpBAECQ operon eliminated this phenotype, suggesting that G2P is a previously unrecognized substrate for the binding protein-dependent Ugp transporter.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Escherichia coli K12 / growth & development
  • Escherichia coli K12 / metabolism*
  • Escherichia coli Proteins / genetics
  • Escherichia coli Proteins / metabolism*
  • Gene Knockout Techniques
  • Glycerophosphates / metabolism*
  • Membrane Transport Proteins / genetics
  • Membrane Transport Proteins / metabolism*
  • Operon


  • Escherichia coli Proteins
  • Glycerophosphates
  • Membrane Transport Proteins