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Review
, 73 (6), 1002-7

Orthostatic Hypertension: A Measure of Blood Pressure Variation for Predicting Cardiovascular Risk

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Review

Orthostatic Hypertension: A Measure of Blood Pressure Variation for Predicting Cardiovascular Risk

Kazuomi Kario. Circ J.

Abstract

Orthostatic hypertension, a measure of blood pressure (BP) variability, is a clinically important pathologic condition associated with the progression of target organ damage and subsequent cardiovascular risk. Orthostatic hypertension precedes hypertension and could be considered as prehypertension if a patient has seated clinic BP <140/90 mmHg. The simple examination of orthostatic BP changes using a self-measured home BP monitoring, through which abnormal pathological conditions can be detected with high reproducibility without the white-coat effect. Orthostatic hypertension is associated with morning hypertension and increased neurohumoral activation; however, the precise mechanism of orthostatic hypertension remains unclear, and accumulation of further clinical evidence is necessary.

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