Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 219 (5), 249-64

The Involvement of Engrailed and Wingless During Segmentation in the Onychophoran Euperipatoides Kanangrensis (Peripatopsidae: Onychophora) (Reid 1996)

Affiliations

The Involvement of Engrailed and Wingless During Segmentation in the Onychophoran Euperipatoides Kanangrensis (Peripatopsidae: Onychophora) (Reid 1996)

Bo Joakim Eriksson et al. Dev Genes Evol.

Abstract

As the putative sister group to the arthropods, onychophorans can provide insight into ancestral developmental mechanisms in the panarthropod clade. Here, we examine the expression during segmentation of orthologues of wingless (Wnt1) and engrailed, two genes that play a key role in defining segment boundaries in Drosophila and that appear to play a role in segmentation in many other arthropods. Both are expressed in segmentally reiterated stripes in all forming segments except the first (brain) segment, which only shows an engrailed stripe. Engrailed is expressed before segments are morphologically visible and is expressed in both mesoderm and ectoderm. Segmental wingless expression is not detectable until after mesodermal somites are clearly distinct. Early engrailed expression lies in and extends to both sides of the furrow that first demarcates segments in the ectoderm, but is largely restricted to the posterior part of somites. Wingless expression lies immediately anterior to engrailed expression, as it does in many arthropods, but there is no precise cellular boundary between the two expression domains analogous to the overt parasegment boundary seen in Drosophila. Engrailed stripes extend along the posterior part of each limb bud, including the antenna, while wingless is restricted to the distal tip of the limbs and the neurectoderm basal to the limbs.

Similar articles

See all similar articles

Cited by 32 PubMed Central articles

See all "Cited by" articles

References

    1. Int J Dev Biol. 2003;47(7-8):479-90 - PubMed
    1. Cell. 1987 Aug 14;50(4):649-57 - PubMed
    1. Dev Biol. 2006 Jan 1;289(1):179-94 - PubMed
    1. Nature. 2008 Apr 10;452(7188):745-9 - PubMed
    1. Evol Dev. 2000 Nov-Dec;2(6):340-7 - PubMed

Publication types

Substances

LinkOut - more resources

Feedback