Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 23 (9), 995-1007

Reproductive Dysfunction in Amenorrheic Athletes and Anorexic Patients: A Review

Affiliations
  • PMID: 1943636
Review

Reproductive Dysfunction in Amenorrheic Athletes and Anorexic Patients: A Review

M J De Souza et al. Med Sci Sports Exerc.

Abstract

Strenuous athletic training and anorexia are associated with a high incidence of amenorrhea. While the physiological and/or psychological stressors that contribute to the development of menstrual dysfunction in these individuals appear to differ, they both involve disorders of the reproductive system that originate in the hypothalamus. The available data suggest that both groups experience alterations in the pulsatile release of GnRH, which in turn produces perturbations in pituitary and ovarian function ultimately leading to menstrual dysfunction. In this review, the reproductive and "stress" hormone profiles in amenorrheic athletes and anorexic patients are compared, and the interaction of these hormonal axes in the occurrence of menstrual dysfunction is discussed.

Similar articles

See all similar articles

Cited by 16 articles

See all "Cited by" articles

Substances

LinkOut - more resources

Feedback