Ethical issues in health research in children

Paediatr Child Health. 2008 Oct;13(8):707-20. doi: 10.1093/pch/13.8.707.
[Article in English, French]


Health research is a moral duty because it is the foundation for evidence-based care by all health care practitioners. Specific Canadian policies and regulations govern the conduct of human research; ethics review of research is required before research is conducted. Research in children poses important challenges with regard to informed consent and assent, vulnerability and potential conflicts of interest (COI). Paediatric health researchers should advocate for research participation by children, while being attentive to mitigating risks.