Renal cell carcinoma, metastatic to the left ventricle

Tex Heart Inst J. 2009;36(1):48-9.

Abstract

Left ventricular metastases from renal cell carcinoma without vena caval or right atrial involvement are extremely rare. Herein, we present the case of a 69-year-old man who had undergone radical nephrectomy for renal cell carcinoma in 1984. Eighteen years thereafter, we discovered metastatic disease in his left ventricle.When the metastasis was identified, the patient had no symptoms other than shortness of breath. He underwent surgical removal of a highly vascular mass from the left ventricular wall and resection of a nodule in the upper right pulmonary lobe. Upon pathologic examination, both tumors were metastatic renal cell carcinomas. The patient recovered uneventfully and was free of cardiac recurrence more than 6 years after the surgery. We describe our treatment of this patient and discuss some current approaches to the treatment of renal cell carcinoma that has metastasized to the heart.

Keywords: Carcinoma, renal cell/complications/pathology/secondary/surgery; coronary disease/etiology/surgery; heart neoplasms/diagnosis/secondary; heart ventricles; neoplasm invasiveness; time factors; treatment outcome.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / secondary*
  • Carcinoma, Renal Cell / surgery
  • Cardiac Surgical Procedures
  • Coronary Angiography
  • Heart Neoplasms / secondary*
  • Heart Neoplasms / surgery
  • Heart Ventricles / pathology
  • Humans
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Lung Neoplasms / secondary
  • Lung Neoplasms / surgery
  • Male
  • Nephrectomy
  • Pneumonectomy
  • Treatment Outcome