Dermatoscopy of blue vitiligo

Clin Exp Dermatol. 2009 Jul;34(5):e125-6. doi: 10.1111/j.1365-2230.2008.03155.x. Epub 2009 Apr 27.


Blue vitiligo is a distinct variant of vitiligo characterized by a blue-grey appearance of the skin, which corresponds histologically with absence of epidermal melanocytes and presence of numerous dermal melanophages. A 23-year-old woman of Indian origin with Fitzpatrick skin type V presented with a 1-month history of normoaesthetic depigmented macules over the right forearm, dorsa of the hands and right areola. The macule over the right forearm had a bluish tinge. A clinical diagnosis of vitiligo vulgaris with blue vitiligo was made. Dermatoscopy of the interface between the blue macule and the hypopigmented macule revealed a linear depigmented macule in the centre with multiple blue dots and absence of epidermal melanin on the side of the blue macule, and reticular pigmentation with a few depigmented macules and scattered blue dots over the side of the hypopigmented macule. Blue vitiligo was described previously in a patient seropositive for human immunodeficiency virus, and believed to represent postinflammatory hyperpigmentation in areas bordering the vitiliginous patches as a result of psoralen ultraviolet A treatment. This case is unusual because of its rarity and the description of the associated dermatoscopical findings.

Publication types

  • Case Reports

MeSH terms

  • Dermoscopy
  • Diagnosis, Differential
  • Female
  • Humans
  • Melanocytes / pathology
  • Skin Pigmentation*
  • Vitiligo / pathology*
  • Young Adult