Maxillary sinus augmentation in humans using cortical porcine bone: a histological and histomorphometrical evaluation after 4 and 6 months

Clin Implant Dent Relat Res. 2011 Mar;13(1):13-8. doi: 10.1111/j.1708-8208.2009.00176.x.

Abstract

Background: Bone substitutes, such as allografts, xenografts, and alloplasts, have been proposed in several augmentation procedures.

Purpose: The aim of the present study was a histologic and histomorphometric evaluation of specimens retrieved 4 or 6 months after sinus augmentation using cortical porcine bone augmentation material.

Materials and methods: A total of 77 specimens, retrieved after 4 and 6 months from augmented sinuses, were used in this study. The specimens were processed to be observed under light microscopy. Histomorphometric measurements were presented as means ± standard deviations.

Results: Most of the particles were surrounded by newly formed bone with large osteocyte lacunae. Histomorphometry showed that, after 4 months, the newly formed bone represented 28%, marrow spaces 36%, the residual graft material 37%, while, after 6 months, the newly formed bone represented 31%, marrow spaces 34%, while the residual graft material was 37%.

Conclusion: The present results show that cortical porcine bone is a biocompatible, osteoconductive biomaterial that can be used for maxillary sinus augmentation procedures without interfering with the normal reparative bone processes.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alveolar Ridge Augmentation / methods*
  • Animals
  • Biocompatible Materials / therapeutic use
  • Bone Regeneration / physiology*
  • Bone Substitutes / therapeutic use*
  • Dental Implantation, Endosseous / methods
  • Female
  • Humans
  • Male
  • Maxillary Sinus / surgery
  • Middle Aged
  • Oral Surgical Procedures, Preprosthetic / methods*
  • Osseointegration / physiology*
  • Swine
  • Time Factors
  • Transplantation, Heterologous
  • Treatment Outcome

Substances

  • Biocompatible Materials
  • Bone Substitutes