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. 2009 May 8;5(5):422-4.
doi: 10.1016/j.chom.2009.05.005.

A Precious Metal Heist

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A Precious Metal Heist

Eric P Skaar. Cell Host Microbe. .
Free article


Nearly all bacterial pathogens require iron to successfully infect their vertebrate hosts. The host molecule lipocalin-2 exploits this by sequestering bacterial siderophores as a mechanism of protection against infection. Raffatellu et al. (2009) show that Salmonella enterica serotype Typhimurium circumvents this through the production of the modified siderophore salmochelin.

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